Bioperine, a patented extract derived from black pepper (Piper nigrum) standardised to contain at least 95% piperine, is widely used as a bioavailability enhancer in dietary supplements. Here are its key benefits based on research:
Benefits of Bioperine
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Enhanced Nutrient Bioavailability
Bioperine significantly improves the absorption of various nutrients, including curcumin, vitamins, and minerals, by inhibiting enzymes that metabolise these compounds and enhancing their bioavailability (Athukuri & Neerati, 2017). -
Synergistic Effects with Curcumin
When combined with curcumin, Bioperine enhances its therapeutic effects by preventing its rapid breakdown, thereby increasing its bioactivity in conditions like inflammation and oxidative stress (Pillai et al., 2021). -
Improved Cognitive and Neurological Health
Piperine has been shown to protect against cognitive decline by enhancing neurotransmitter function and reducing oxidative stress, which is beneficial in neurodegenerative disorders (Majeed et al., 2023). -
Cardiovascular and Anti-Atherosclerotic Effects
Research highlights the role of Bioperine in supporting cardiovascular health by reducing foam cell formation and inflammation in atherosclerosis models (Pillai et al., 2021). -
Antioxidant and Anti-Inflammatory Properties
Bioperine enhances the body’s antioxidant defences, reducing oxidative damage and inflammation, particularly in conditions like chronic obstructive pulmonary disease (Sharafkhaneh et al., 2013). -
Support for Metabolic Health
Studies suggest that Bioperine improves metabolic function by enhancing thermogenesis and lipid metabolism, which can aid in weight management (Majeed et al., 2023).
Conclusion
Bioperine is a potent bioavailability enhancer with additional health benefits such as improved nutrient absorption, anti-inflammatory effects, and support for cardiovascular and neurological health. Its ability to enhance the efficacy of co-administered compounds makes it a valuable ingredient in various therapeutic and health-promoting formulations.